马小京

马小京，为上海交通大学"盛毓绶"冠名讲席教授。

• 中文名称 马小京
• 国籍 中国
• 民族 汉
• 职业 教师
• 职称 教授

研究生涯

　　1987年获英国爱丁堡大学分子遗传学专业博士学句巴善甲跑雨款本办该位，先后在美国宾夕法尼亚大学担任高级研究员、康奈尔大学担任终身教授，长期从事探索免疫学领域的基础研究，在揭示免疫反应细胞和分子作用机制及开创新的探测技术方法手段方面取得了突出成绩。在Nature Immunology、Immun来自ity、J. Experimental Medicine, J.Immunology等高水平国际期刊杂志发表SCI间实局孔史百论文80余篇，相关研究成果的独特与创新性被Nature和Cell、Nature Reviews Immunology等进行专题报导和评论。曾荣获Young Investigators Award b360百科y International Cytokine Society、Howard Temin Award (NCI/NIH)等奖励。

发表论文

　　Original research articles

　　1. Yin, F, Banerjee, R, Thomas, B, Zhou, 持烟最讨冷组眼危P, Qian, L, J编苏ia, T, Ma, X, Ma, Y, Iadecola, C, Beal, MF, Nathan, Cand Ding, H. 2010. Exaggerated Inflammation, Impaired Host Defense and Neuropathology in Progranulin-Deficient Mice. J. Exp. Med. 207(1):117-128.

　　2. Jiao, X., Katiyar, S., Willmarth, NE, Liu县止你座攻肉离争调, M., Flomenberg, N., Ma, X., Lisanti, MP, Pestell, RG. 2010. C-jun induce令市半员s mammary epithelial cellular invasion and breast cancer stem cell expansion. J. Bio关汉集工因放伯剧单l. Chem. 285(11):8218-8226.

　　3. Kang, X, Kim, HJ, Ramirez, M, Salameh, S, Ma, X. 2010. The Septic Shock-associated IL-10 -1082 A>G Polymorphism Mediates Allele-specific Transc费鸡故抗左练微触部重调ription via Poly ADP-ribose Pol庆审执创是亚ymerase 1 in Macrophages Engu促亚住厂死号迫需器组lfing Apoptotic Cells. J. Immunol. 184:371又8-3724.

　　4. Zha将药农叶层贵ng, Y. Ma, X. 2010. Triptolide Inhibits IL-12/IL-23 Gene Expression in Antigen-presenting Cells via CCAAT/enhancer-Binding Protein Alpha. J. Immunol. 184:3866-3877.

　　5. Noguchi, E., Homma, Y., Ka须微投电ng, X., Netea, MG, and Ma, X. 2009. A Crohn's disease–assoc害别立日否仅和亮物iated NOD2 mutation suppresses transcription of human IL10 by inhib林却项iting activity of the 打民个略京次厚氧高圆nuclear ribonucleoprotein hnRNP-A1. Nature Immunology. 10(5):471-479.

　　6. Leavenworth JW, Ma X, Mo YY, Pauza ME. SUMO conjugation contrib延系展急坐长呢部确utes to immune deviation in nonobese diabet侵右转换ic mice by suppressing c-Maf transactivation of IL-4. 2009. J Immunol. 2009 Jul 15;183(2):1110-1119.

　　7. Jayakumar, A., Widenmaier, R., Ma, X., and McDowell, MA. 2008. Transcriptional inhibition of interleukin-12 promoter activity in leishmania spp.-infected macrophages. J. Parasitol.,94(1):84–93.

　　8. Chung, E., Liu, J., Homa, Y., Zhang,Y., Brendolan, A., Saggese, M., Han, J., Silverstein, R., Selleri, L., . 2007. Interleukin-10 Expression in Macrophages during Phagocytosis of Apoptotic Cells Is Mediated by homeoproteins Pbx-1 and Prep-1. Immunity.27:952-964.

　　9. Liu, J., Guan, X., X. Ma. 2007. Regulation of IL-27 p28 gene expression in macrophages through MyD88- and Interferon-g-mediated pathways. J Exp Med. 204:141-152.

　　10. Park-Min, K., Serbina, N., Yang, W., X. Ma, Krystal, G., Neel, BJ, Nutt, SL, Hu, X., and Ivashkiv, LB. 2007.FcγRIII-Dependent Inhibition of Interferon-γ Responses Mediates Suppressive Effects of Intravenous Immune Globulin. Immunity. 26, 67-78.

　　11. Chung, EY, Liu, J., Zhang, Y., and X. Ma. 2007. Differential Expression in Lupus-associated IL-10 Promoter Single-nucleotide Polymorphisms Is Mediated by Poly(ADP-ribose) Polymerase 1. Genes & Immunity. 8(7):577-589.

　　12.Homma, Y., Cao, S., Shi, X., and X. Ma. 2007. The Th2 transcription factor c-Maf inhibits IL-12p35 gene expression in activated macrophages by targeting NF-kB nuclear translocation. J. Interferon & Cytokine Res. 27(9):799-808.

　　13.Werts, C., le Bourhis, L., Liu, J., Magalhaes, JG., Fritz, JH., Stockinger, S., Decker, T., Philpott, DJ., Ma, X., and Girardin. SE. 2007. Nod1 and Nod2 induce CCL5/RANTES through the NF-κB pathway. Eur. J. Immunol. 37(9):2499-2508.