修志龙

修志龙，男，毕业于大连理工大学，博士，大连理工大学教授来自、博士生导师、硕士生导师。

• 中文名 修志龙
• 毕业院校 大连理工大学
• 学位/学历 博士
• 专业方向 生物化工
• 任职院校 大连理工大学

人物经历

教育经历

　　1979.9-1982.8 山东省海阳一中

　　1998.9-2000.7 大连理工大学生物化工博士

　　1物苦艺些亲但987.9-1990.7 大连理工大学生物化工硕士

　　19代客节82.9-1987.7 清华大学化学工程学士

工作经历

　　2010.3至今 大连理工大学生命科学与技术学院教授

　　2002.10-2010.3 团伟松染后算大连理工大学环境与生命学院教授

　　1997.10-2002.10 大连理工大学化工学院副教授

　　1992.12-1997.10 大连理工大学化工学院讲师

　　1990.3-1992.12 大连理工大学化工学院助教

学术成果

论文成果

　　[1]Pan, 快粮伟剂色提检封Duo-Tao,Wang, Xu-Dong,Shi, Hong-Yan,Yuan, De-Chen缺制g,Xiu, Zhi-Long.Ensemble op底刑器静散内外机认timization of microb来自ial conversion of glycerol into 1, 3-propanediol by Klebsiella pneumoniae[J],JOURNAL OF BIOTECHNOLOGY,2019,301:68-78

你坏　　[2]Dong, Yue-Sheng,Yang, Fan,Liu, Wen360百科-Cai,Wang, Xu-Dong,Xing, Yan,Xi念刚期还而海河u, Zhi-Long.Separation and purification of wortmannilactone analogues by three-liquid-phase salting-out extraction cou宜读pled with column chromatography[J],SEPARATION AND PU矛息连开宽物RIFICATION TECHNOLOGY,2019,224:397-404

　　[3]Li, Zhen,Yan, Ling,Zhou, Jinjie,Wang, Xiaoli,Sun, Yaqin,Xiu, Zhi-Long.Two-step salting-out extraction of 1,3-propanediol, butyric acid and acetic acid from fermentation broths[J],SEPARATION AND PURIFICATION TECHNOLOGY,2019,209:246-253

　　[4]Yuan Yuyu,Qu Kunli,Tan Demeng,Li Xiaoyu,Wan画又g Lili,Cong Cong,Xiu Zhilong,Xu Yongping.Isolation and characterization of a bacteriophage and its potential to disrupt 双吸想multi-dr科完反专感素四矛文厚去ug resistant Pseudomonas ae权种师冲育使磁ruginosa biofilms[J],Microbial pathogenesis,2019,128:329-336

　　[5]Dai Jianying,Wang Zhuangfei,Xiu Zhi-Long.High production of optically pure (3R)毫杂-acetoin by a newly isolated marine strain of Bacillus subtilis CGMCC 13141[J],Bioprocess and biosystems engineering,2019,42(3):475-483

　　[6]Pan, Duo-Tao,Wang, Xu-Dong,Shi, Hong-Yan,Yuan, De-Cheng,Xiu, Zhi-Long.Dynamic flux balance analysis for microbial c头专身议可显曲烈样onversion of glycerol into 1,3-propanediol by Klebsiella pneumoniae[J],BIOP宜普院ROCESS AND BIOSYSTEMS ENGINEERING,2018,41(12):1793-1805

　　[7]Wang, Xu-Dong,Wei, Ning-Ning,Wang, Shu-Chang,Yuan, Heng-Li,Zhang, Feng-Ying,Xiu, Zhi-Long.Kinetic 打速局Optimization and Scale-Up of Site-Specific Thiol-PEGylation of Loxenatide from Laboratory to Pilot Scale[J],INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,2018,57(44):14915-14925

　　[8]Sun, Yaqin,Zhang, Shuangshuang,Zhang, Xingxing,Zheng, Yafeng,Xiu, Zhilong.Ionic liquid-based sugaring-out and salting-out extraction of succinic acid[J],SEPARATION AND PURIFICATION TECHNOLOGY,2018,204:133-140

　　[9]Zhou, Jin-Jie,Shen, Jun-Tao,Wang, Xiao-Li,Sun, Ya-Qin,Xiu, Zhi-Long.Stability and oscillatory behavior of microbial consortium in continuous conversion of crude glycerol to 1,3-propanediol[J],APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2018,102(19):8291-8305

　　[10]Dou, Shaohua,Chi, Naiyu,Zhou, Xinshang,Zhang, Qingfang,Pang, Fei,Xiu, Zhilong.Molecular cloning, expression, and biochemical characterization of a novel cold-active alpha-amylase from Bacillus sp dsh19-1[J],EXTREMOPHILES,2018,22(5):739-749

　　[11]Wang, Xudong,Wang, Shuchang,Pan, Duotao,Qin, Kairong,Yuan, Hengli,Zhang, Fengying,Sun, Yundong,Xiu, Zhilong.Combined optimization of N-terminal site-specific PEGylation of recombinant hirudin using response surface methodology and kinetic analysis[J],ENGINEERING IN LIFE SCIENCES,2018,18(8):611-621

　　[12]Dai, Jianying,Wang, Hui,Li, Yan,Xiu, Zhi-Long.Imidazolium ionic liquids-based salting-out extraction of 2,3-butanediol from fermentation broths[J],PROCESS BIOCHEMISTRY,2018,71:175-181

　　[13]Sun, Ya-Qin,Shen, Jun-Tao,Yan, Ling,Zhou, Jin-Jie,Jiang, Li-Li,Chen, Yang,Yuan, Jin-Long,Feng, Enmin,Xiu, Zhi-Long.Advances in bioconversion of glycerol to 1,3-propanediol: Prospects and challenges[J],PROCESS BIOCHEMISTRY,2018,71:134-146

　　[14]Zhang, Bowei,Xiu, Zhilong,Ma, Baiping,Yu, Liyan,Dong, Yuesheng,Sun, Wenlong,Yu, Na,Sun, Jin,Yu, Xiaoxia,Li, Xia,Xing, Yan,Yan, Dong,Ding, Qianzhi.Anti-diabetic effect of baicalein is associated with the modulation of gut microbiota in streptozotocin and high-fat-diet induced diabetic rats[J],JOURNAL OF FUNCTIONAL FOODS,2018,46:256-267

　　[15]Yan, Ling,Sun, Ya-Qin,Wang, Xu-Dong,Fu, Hong-Xin,Mu, Ying,Xiu, Zhi-Long.Partition behavior of monocarboxylic acids in salting-out extraction systems of monohydric alcohols and dipotassium phosphate[J],SEPARATION AND PURIFICATION TECHNOLOGY,2018,199:351-358

　　[16]孜力汗,贾凌云,杨君,修志龙,包永明,袁文杰,牟英,唐颖.通过科研与教学的结合建设生物工程专业校内实习实训基地[J],化工高等教育,2018,35(3):75-81

　　[17]胡春燕,王旭东,秦超,董悦生,修志龙.克拉维酸钾一步结晶工艺优化[J],高校化学工程学报,2018,32(4):910-917

　　[18]Dong, Zhenyu,Tan, Bing,Zhang, Yuduo,Yuan, Jinlong,Feng, Enmin,Yin, Hongchao,Xiu, Zhilong.Strong stability of an optimal control hybrid system in fed-batch fermentation[J],INTERNATIONAL JOURNAL OF BIOMATHEMATICS,2018,11(4)

　　[19]Zhao Shan,Yang Fan,Liu Yang,Sun Dongsheng,Xiu Zhilong,Ma Xiaojun,Zhang Ying,Sun Guangwei.Study of chemical characteristics, gelation properties and biological application of calcium pectate prepared using apple or citrus pectin.[J],International journal of biological macromolecules,2018,109:180-187

　　[20]Xing, Yan,Chen, Chaonan,Sun, Wenlong,Zhang, Bowei,Sang, Yuanbin,Xiu, Zhilong,Dong, Yuesheng.An environment-friendly approach to isolate and purify glucan from spent cells of recombinant Pichia pastoris and the bioactivity characterization of the purified glucan[J],ENGINEERING IN LIFE SCIENCES,2018,18(4):227-235

专利成果

　　一种具有协同作用的α-糖苷酶抑制剂组合物及其应用

　　一种基于生长耦联的底物流加发酵生产1,3-丙二醇的方法

　　一种微生物转化法制备属于皂素的方法

　　一种改善高脂高糖饮食并发症的药物组合物及其应用

　　一种硅酸盐催化制备生物柴油的方法

　　一种从克雷伯氏杆菌发酵液中提取1，3-丙二醇的方法

著作成果

　　代谢工程的途径分析与优化

　　生物化学

　　成功的科研写作

　　生物工程与技术导论

　　多级生物加工系统优化原理与技术，第五章 1, 3-丙二醇生物合成过程及其优化与控制

　　Bioprocessing of renewable resources to commodity bioproducts

科研项目

　　基于生长和代谢特征的底物流加发酵生产1,3-丙二醇的控制方法, 国家自然科学基金项目, 2018/07/20-2030/03/31, 进行

　　微生物发酵甘油年产一万吨1,3-丙二醇, 企事业单位委托科技项目, 2018/06/29-2019/12/31, 进行

　　抗生素废酸水处理技术, 企事业单位委托科技项目, 2016/12/30-2018/06/30, 进行

　　海洋微生物菌群的特性及其工业应用, 其他课题, 2016/11/28, 进行

　　三种青霉素酰化酶的盐析萃取技术, 自选课题, 2016/07/08-2016/12/30, 进行

　　聚乙二醇洛塞那肽工艺优化及作用机制研究, 自选课题, 2016/07/09-2017/07/19, 完成