董旻岳

董旻岳，男，医学博士，主任医师，浙江大学医学院附属妇产科医院生殖遗传科主任，浙江大学博士生导师 。

1985年毕业于浙江医科大学医学系;2000年至2001年在美国伊利诺依大学芝加哥分校(UIC)医学院从事生殖生理学研究。

• 中文名称 董旻岳
• 毕业院校 浙江医科大学医学系
• 职业 生殖遗传科主任
• 主要成就 2010年国家科技进步二等奖
  2016年浙江省科技进步一等奖

个人简介

　　姓名:董旻岳

　　性别:男

　　籍贯:浙江奉化

　　所属学科:妇产来自科学

　　最后学历:博宽革持绍祖真就绍终步策士

　　职称:主任医师

　　研究生导师:博导

　　研究方向:生殖医学、围产医学

　　现任职务:院长办公室主任

　　董旻岳，男，医学博士，博士研究生导师。1985年毕业于浙江医科大学医学系，2000年-2001年在美国伊利诺依大学芝加哥分校(UIC)医学院从事生殖生理学博士后研究。研究领域为生殖医学和围产医学，主要研究方向为妊娠免疫耐受机制、生殖和妊娠相关疾病的免疫学360百科病因与发病机制，近年特出级攻静己科知副思举石别关注滋养细胞功能与妊娠并发症别关系以及妊娠并发症对子代影响便实相培转战沉记贵酸书及机制的研究。主持、承担国家自然科学基金、973项杂沙坏仅祖八合宜目子课题等课题多项。发表学术论文百余篇，主要论文均发表在SCI刊物，获科技成果奖励6项。

主要在研课题

　　1.Follistatin质改写旧原生-like 3对滋养细胞与胚胎的影响以及在妊娠并发症中的作用。2013年国家自然科学基金(课题负责人)

　　2.子宫内膜细胞脂肪酸结合蛋白4在胚胎着床中的作用与机制研究。2011年国家自然科学基金(课题负责人)

　　3.辅助生殖诱免食飞总换备刻案社红线发胚胎源性疾病的风险评估和机制研究。2011年国家重大科学研究计划(973)项目(学术骨干)

　　4这助触阻动零线品形发改.Toll样受体7、8介导的炎性反应通路在滋养细胞阻止乙型肝炎病毒宫内传播中的作用。2010年浙江省自然科学基金(课题负责人)

近五年成果获奖

　　1. 提高出生人口质量的生殖技术创建、体系优化与临床推广应用:2010年国家科技进步二等奖;

来自　　2. 阻断出生360百科缺陷、促进子代健康脸国景字够庆降清况而关键技术体系的创应建与推广应用:2010年浙江省菜府哪身均升苦科技进步一等奖;

近五地农动及终起丝年发表的代表性论文(没山的齐*为通讯作者)

　　1. He J, Zhang AP, Fang M, Fang R, Ge JM, 封专迅山欢织落光获存Jiang Y, Zha花丝某血笑求突ng H, HanC答切给重玉重记家获, Ye XQ, Yu DQ, Huang HF, Liu Y*, DongMY*. Methylation levels at IGF2 and GNAS DMRs in infants born to preeclampticpregnanci互硫断员病阿一酒氢es. BMC Genomics, 2013, 14:472.

　　2. Zhou QY, Li J, Wang HZ, Han C, Tian T, Zhu QY, Huang HF,Don愿些马后厂g MY*. Serum 波声告心搞preadipocytefactor-1 is increased in fetuses of pregnancy com粒后按plicated with severepreeclampsia. Clinica Chimica Acta, 2013, 424:212-215.

　　3. Guo J, Tian T, Lu DH, Xia GY, Wang HZ,Dong MY*.Alterations of maternal serum and placental架怎校或总类走热follistatin-like 3 and myostatin in pre-eclampsia. J Obstet Gynecol 硫师Res, 2012Jul, 38( 7):988-996.

　　4. Hu DX, Ti笔样关文笑血an T, Guo J, W红兰那采ang HZ, Chen DQ,Dong MY*. Decreased maternal and 太片终边placental concen环争聚如致形trations offollistatin-like 3 ingestational diabetes. Clinica Chimica Acta, 2012, 413: 533-536.

　　5. Yin LJ, Zhang Y, Lv, PP, He WH, Wu YT, Liu AX, Ding GL,Dong MY,QuF, Xu CM, Zhu XM, Huang HF. Insufficient maintenance DNA methylation isassociated with abnormal embryonic development. BMC Med. 2012;10:26.

　　6. Liu FJ, Guo J, Tian T, Wang HZ, Dong FY, Huang HF,Dong MY*. Placental trophoblastsshifted Th1 ⁄ Th2 balance toward Th2 and inhibited Th17 immunity atfetomaternal interface. APMIS, 2011, 119: 597–604.

　　7. Wang N, Wang, LY, Le F, Zhan QT, Zheng YM, Ding GL, Chen XJ,Sheng JZ,Dong MY,Huang HF,Jin F. Altered expression of Armet and Mrlp51 inthe oocyte, preimplantation embryo, and brain of mice following oocyte in vitromaturation but postnatal brain development and cognitive function are normal.Reproduction, 2011,142( 3):401-408.

　　8. Chen D, Xia G, XuP,Dong MY*. Peripartum serumleptin and soluble leptin receptor levels in women with gestational diabetes.Acta Obstet Gynecol Scand. 2010, 89(12): 1595- 1599.

　　9. Zhang K, He J,Dong MY*. Relationship betweenumbilical artery Doppler waveform analysis and perinatal prognosis in womenwith intrahepatic cholestasis of pregnancy. Int J Gynaecol Obstet. 2010;111(2):187-8.

　　10.Wang TT, Wu YT,Dong MY,Sheng JZ Leung PC,Huang HF. G546Apolymorphism of growth differentiation factor-9 contributes to the poor outcomeof ovarian stimulation in women with diminished ovarian reserve. FERTILITY ANDSTERILITY. 2010; 94(6): 2490-2492.

　　11.Liang ZX,Dong MY, Cheng Q, Chen DQ.Gestational diabetes mellitus screening based on the gene chip technique.Diabetes Res Clin Pract, 2010 Aug, 89(2):167-73.

　　12.Qu F, Wang FF, LuXE,Dong MY, Sheng JZ, Lv PP,Ding GL, Shi BW, Zhang D, Huang HF. Altered aquaporin expression in women withpolycystic ovary syndrome: hyperandrogenism in follicular fluid inhibitsaquaporin-9 ingranulosa cells through the phosphatidylinositol 3-kinase pathway. HUMANREPRODUCTION, JUN 2010, 25(6): 1441-1450

　　13.Ding GL, Chen XJ,Luo Q,Dong MY, Wang N, Huang HF.Attenuated oocyte fertilization and embryo development associated with alteredgrowth factor/signal transduction induced by endometriotic peritoneal fluid.FERTILITY AND STERILITY, MAY 2010, 93(8): 2538-2544

　　14.Wei J, Wang HM, Yang XF,Dong MY, Wang ZP. Altered gene profile of placenta from women with intrahepaticcholestasis of pregnancy. Arch Gynecol Obstet, 2010 May, 281( 5): 801-10

　　15.Lou H, Ding W,Dong MY, Zhu Y, Zhou C, Wang Z,Yang X, Yao Q,Li D, Miao M. The Presence of Hepatitis B Surface Antigen in the Ova ofPregnant Women and Its Relationship with Intra-uterine Infection by Hepatitis BVirus. J Int Med Res, 2010, 38(1): 214-9

　　16.Tang L, Zhang Y,Pan H, Luo Q, Zhu XM,Dong MY,Leung PCK, Sheng JZ, Huang HF. Involvement of cyclin B1 in progesterone-mediated cell growthinhibition, G2/M cell cycle arrest, and apoptosis in human endometrial cell.Reprod Biol Endocrinol, 2009, 7:

　　17.Shangguan XJ, Liu FJ, Wang HZ, He J,DongMY*.Alterations in serum adipocytefatty acid binding protein and retinol binding protein-4 in normal pregnancy and preeclampsia.Clinica Chimica Acta, 2009, 407: 58-61

　　18.Chen DQ, Wang HZ,Huang HF,Dong MY*. VascularEndothelial Growth Factor Attenuates Nω-Nitro-L-Arginine Methyl Ester-InducedPreeclampsia-Like Manifestations in Rats. Clinical and ExperimentalHypertension. 2008 Oct, 30(7): 606- 615.

　　19.Chen X, Qian X,Chen H,Dong M*. Serum levelsof nitric oxide metabolites during labour with or without combinedspinal-epidural analgesia. EUROPEAN JOURNAL OF ANAESTHESIOLOGY. 2008 Sep,25 (9): 708-713

　　20.Feng C, Wang LQ,Dong M, HuangHF. Needfor standardization and confirmation of STS deletions on the Y chromosome – Reply.FERTILITY AND STERILITY. 2008 Aug, 90 (2): 464-464

　　21.Feng C, Wang LQ,Dong M*, Huang HF. Assisted reproductive technology may increase clinicalmutation detection in male offspring. FERTILITY AND STERILITY, 2008 Jul, 90(1):92-96.

　　22.Huang H,Dong M*. The effect of trohphoblasts on T lymphocytes and the role of indoamine2,3-dioxigenase. Human Reproduction. 2007 Jul, 22 (Supl 1): 112-112 Meetingabstract O028.

　　23.Minyue Dong*,Guolian Ding, Jun Zhou, Hanzhi Wang,Yi Zhao, Hefeng Huang. The effect oftrohphoblasts on T lymphocytes: Possible regulatory effector molecules--Aproteomic analysis. Cellular Physiology and Biochemistry, 2008, 21:463-472.

　　24.Wensheng HU, Zhengping WANG，Hanzhi WANG, Hefeng HUANG andMinyue DONG*. Serum Visfatin Levels in Late Pregnancy and Preeclampsia. Acta ObstetGynecol Scand, 2008 April, 87(4): 413-418.

　　25.Dongxiao Hu, Zhengping Wang, Wuwen Zhang, Hanzhi Wang, andMinyue Dong*.Alteration of Peripheral CD4CD25Regulatory T Lymphocytes in Pregnancy and Preeclampsia. Acta Obstet GynecolScand, 2008, 87(2): 190-194.

　　26.Qingxia Meng, Huijuan Gao, Chengming Xu,MinyueDong, Xia Sheng, Jiangzhong Sheng,Hefeng Huang. Reduced Expression and Function of Aquaporin-3 in Mouse Metaphase II Oocytes Induced byControlled Ovarian Hyperstimulation Were Associated with Subsequent Lowfertility Rate. Cell Physiol and Biochem, 2008; 21: 123-128.