蒋卫

蒋卫，武汉大学医学研究院教授，专 业:细胞生物学、占还纪左林模发育生物学，研究方向:干细胞生物学和表观遗传调控

• 中文名称 蒋卫
• 国籍 中国
• 民族 汉族
• 毕业院校 北京大学
• 学位/学历 博士

人物经历

教育经历

　　2001-20来自05 北京大学生命科学学院生物科学专业，学士

　　2005-201轮子料0 北京大学生命科学学院细胞生物学专业，博士

工作经历

　　2011-2012 美国霍华德休斯医学研究所及北卡罗莱纳大学教堂山分校，博士后

　　2012-2015 美国霍华德休斯医学研究所及哈佛医学院、波士顿儿童医院，博士后

　　2015- 武汉大学医学研究铁良通应密院教授、中南医院特聘研究员

研话女段研难究方向

　　干细胞分化

　　表观遗传学调控

　　长非编码RNA

　　疾病模型

　　糖尿病

获奖记录

　　HMS Epigenetics Initiative Travel Grant (2015);

　　Juvenile Diabetes Research Founda来自tion (JDR杨宽F) Postdoc问刻仅toral Fel360百科lowship (2012-2015);

　　Beta Cell Biology Co真浓绿居讲个重证移nsortium (BCBC) Investigator Retr个觉走厂土革管联负料富eat, Scholarship (2012, 2013);

发表论文概况

　　已在国际刊物发表论文 40 多篇，被 SCI 引用 200合指0 余次，第一作者论文单篇最高被引用 300 余次。

代表性论文

　　( 20 out of 40+ )( co-first authors;*co-r因例系防文坐esponding aut当越突绍十妒选胡hors)

1. Song Ding, Xianchun Lan, Yajing Meng, Chenchao Yan, Mao Li, Xiang Li*, Jian Chen*, Wei Jiang*. (2021). CH快物略曾民集D8 safeguards early neuroectoderm differentiation 护导稳染际烈出配境帮in human E煤建SCs and protects from apoptosis during neurogenesis. Cell Death & Disease. (in press)
2. Yajing Meng, Tianzhe Zha按乱氧总ng, Ran Zheng, Song Ding, Jie Yang, Yingan Jiang*, Wei Jiang*. (2021). 局执皮映Depletion of de封县角角肉放企毛愿位美methylase KDM6 en快优季能黑等hances early ne准说果育uroectoderm commitment of human PSCs. Frontiers in Cell a施短沿衡鱼艺门效nd Developmental Biology 9:702462. DOI: 脱采争通一职10.3389/fcell.2021.702462.
3. Ran Zheng, Ting Geng, Dan-Ya Wu, Tianzhe Zhan居士问导渐局齐把速g, Hainan He, Hai-Ning Du, Donghui Zhang*, Yi-Liang Miao*, Wei Jiang*. (2021). Derivation of feeder-free human extended pluripotent stem cells. Stem Cell Reports 16(7):1686-1696. DOI: 10.1016/j.stemcr.2021.06.001.
4. Pei Lu, Mao Li, Donghui Zhang*, Wei Jiang*. (2021). Lnc-ing pluripotency maintenance and early differentiation in human pluripotent stem cells. FASEB Journal 35(4): e21438. DOI: 10.1096/fj.202002278R.
5. Ran Liu, Kaiyu Qian, Yu Xiao*, Wei Jiang*. (2021). Generation of two induced pluripotent stem cell lines from blood cells of a prostate cancer patient carrying germline mutation in CHEK2. Stem Cell Research. 53:102299. DOI: 10.1016/j.scr.2021.102299.
6. Jie Yang, Pei Lu, Mao Li, Chenchao Yan, Tianzhe Zhang, Wei Jiang*. (2020). GATA6-AS1 Regulates GATA6 Expression to Modulate Human Endoderm Differentiation. Stem Cell Reports 15(3):694-705. DOI: 10.1016/j.stemcr.2020.07.014.
7. Jie Yang, Wei Jiang*. (2020). The Roles of SMAD2/3 in Human Embryonic Stem Cells. Frontiers in Cell and Developmental Biology 8:653. DOI: 10.3389/fcell.2020.00653.
8. Yangyang Yu, Wei Jiang*. (2020). Pluripotent Stem Cell Differentiation as an Emerging Model to Study Human Prostate Development. Stem Cell Research & Therapy 11(1):285. DOI: 10.1186/s13287-020-01801-9.
9. Mengtian Tan, Lai Jiang, Yinglei Li, Wei Jiang*. (2019). Dual inhibition of BMP and WNT signals promotes pancreatic differentiation from human pluripotent stem cells. Stem Cells International 2019: 5026793. DOI: 10.1155/2019/5026793.
10. Ting Geng, Donghui Zhang, Wei Jiang*. (2019). Concise Review: Epigenetic Regulation of Transition among Different Pluripotent States. Stem Cells 37(11):1372-1380. DOI: 10.1002/stem.3064.
11. Yinglei Li, Wei Jiang*. (2019). The path and surface marker of SC-β cells. Science Bulletin 64(16), 1122-1124. DOI: 10.1016/j.scib.2019.06.018.
12. Xiaojuan Su, Mengtian Tan, Bo Duan, Jie Cai*, Wei Jiang*, Lina Zhang*. (2019). Hierarchical microspheres with macropores fabricated from chitin as 3D cell culture. Journal of Materials Chemistry B 7(34), 5190-5198. DOI: 10.1039/c9tb01046g.
13. Zhang D*, Jiang W*. (2015). From one-cell to tissue: reprogramming, cell differentiation and tissue engineering. Bioscience 65 (5): 468-475. DOI: 10.1093/biosci/biv016.
14. Jiang W*, Liu Y, Liu R, Zhang K, Zhang Y*. (2015). LncRNA DEANR1 facilitates human endoderm differentiation by activating FOXA2 expression. Cell Reports 11(1), 137–148. DOI: 10.1016/j.celrep.2015.03.008.
15. Jiang W*, Zhang D, Bursac N, Zhang Y*. (2013). WNT3 is a biomarker capable of predicting definitive endoderm differentiation potential of hESCs. Stem Cell Reports 1 (1), 46-52. DOI: 10.1016/j.stemcr.2013.03.003.
16. Jiang W, Wang J, Zhang Y*. (2013). Histone H3K27me3 demethylases KDM6A and KDM6B modulate definitive endoderm differentiation from human ESCs by regulating WNT signaling pathway. Cell Research 23(1), 122-130. DOI: 10.1038/cr.2012.119.
17. Jiang W, Sui X, Zhang D, Liu M, Ding M, Shi Y*, Deng H*. (2011). CD24: A novel surface marker for PDX1-positive pancreatic progenitors derived from human embryonic stem cells. Stem Cells 29(4):609-617. DOI: 10.1002/stem.608.
18. Zhang D, Jiang W, Liu M, Sui X, Yin X, Chen S, Shi Y, Deng H*. (2009). Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells. Cell Research 19(4):429-438. DOI: 10.1038/cr.2009.28. 封面文章;被同期专文评述关注;获赛诺菲 - 安万特 Cell Research 2009 年度最佳研究论文奖
19. Jiang W, Bai Z, Zhang D, Shi Y, Yong J, Chen S, Ding M, Deng H*. (2008). Differentiation of mouse nuclear transfer embryonic stem cells into functional pancreatic beta cells. Diabetologia 51:1671-1679. DOI: 10.1007/s00125-008-1065-1.
20. Jiang W, Shi Y, Zhao D, Chen S, Yong J, Zhang J, Qing T, Sun X, Zhang P, Ding M, Li D*, Deng H*. (2007). In vitro derivation of functional insulin-producing cells from human embryonic stem cells. Cell Research 17:333-344. DOI: 10.1038/cr.2007.28.